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ESCMID Global 2024
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Guidelines
From the archive: ECCMID and more before 2010
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17 April 2023 - P2106
In vitro microbiologic activity of WCK 4282 (high-dose cefepime/tazobactam combination) against OXA-1-harbouring, ESBL-phenotype E. coli and K. pneumoniae clinical isolates
Thomas Lodise, Yuvasri Manokaran, Yamuna Devi Bakthavachalam, Balaji Veeraraghavan, Anouk Edwina Muller
17 April 2023 - P2099
WCK 4282 (cefepime/tazobactam, FEP/TAZ): determination of tazobactam pharmacodynamic targets (PDTs) in presence of cefepime employing piperacillin/tazobactam-resistant ESBL or OXA-48-like-expressing Enterobacterales
Anouk Edwina Muller, Sanne Van Den Berg, Kushal Umarkar, Pavan Tayde, Melroy Tellis, Ashwani Kumar, Rajesh Chavan, Vineet Zope, Swapna Takalkar, Hariharan Periasamy
16 April 2019 - P2769
Selection of EUCAST disk potency for WCK 4282 (cefepime-tazobactam, FEP-TAZ) susceptibility testing against Enterobacterales and Pseudomonas aeruginosa
Sachin Bhagwat, Jiji Joseph, Erika Matuschek, Raju Thombre, Hemant Khande, Suyog Vaidya, Snehal Palwe, Hariharan Periasamy, Helio S. Sader, Jane Ambler, Mahesh Patel, Gunnar Kahlmeter
15 April 2019 - P1970
Population pharmacokinetics and dose adjustment of cefepime/tazobactam high dose (WCK4282) in patients with intermittent haemodialysis
Anouk Edwina Muller, Sachin Bhagwat, Mahesh Patel, Johan W. Mouton
14 April 2019 - P1174
Antimicrobial activity of high-dose extended infusion cefepime-tazobactam (WCK 4282) tested against Gram-negative organisms collected from medical centres located in Europe and the Asia-Pacific region in 2018
Helio S. Sader, Mariana Castanheira, Jennifer Streit, Leonard Duncan, Robert Flamm
25 April 2017 - OS1016
WCK 4282 [high-dose Cefepime (FEP)-Tazobactam (TAZ)]: In-vivo PK/PD studies identifying TAZ threshold concentrations (CT) against AmpC P. aeruginosa (PA)
Sachin Bhagwat, Swapna Takalkar, Kushal Umarkar, Jaykumar Satav, Amol Kulkarni, Pavan Tayde, Rajesh Chavan, Mahesh Patel
24 April 2017 - P1303
Safety and Pharmacokinetics of Single and Multiple Intravenous Doses of WCK 4282 (Cefepime and Tazobactam) in Healthy Volunteers
Rakesh Chugh, Ashima Bhatia, Mugha Gupta, Piotr Iwanowski, H David Friedland
11 April 2016 - P1259
WCK 4282 (high-dose cefepime-tazobactam) – assessment of synergy through time-kill curve and MIC determination against Pseudomonas aeruginosa producing OXA and VEB beta-lactamases
Mahesh Patel, Patel Mahesh, El-Bouseary Maisra, J. Prashant, H. Khande, S. Bhagwat, M. Patel
11 April 2016 - P1260
Safety, tolerability and pharmacokinetics of WCK 4282 (fep-taz) in healthy adult subjects
Ashima Bhatia, Sahm Daniel, Bhatia Ashima, A. Bhatia, R. Chugh, M. Gupta, P. Iwanowski
11 April 2016 - P1261
In vitro activity of WCK 4282 (high-dose cefepime-tazobactam) against resistant subsets of Enterobacteriaceae collected worldwide (2014)
Helio S. Sader, Sader Helio, El-Bouseary Maisra, H. Sader, P. Rhomberg, M. Castanheira, R. Jones
11 April 2016 - P1262
Antimicrobial activity of WCK 4282 (high-dose cefepime-tazobactam) tested against Gram-negative organisms from medical centres located in Europe and the Asia-Pacific region
Helio S. Sader, Huband Michael, Sader Helio, H. Sader, D. Farrell, R. Flamm, M. Castanheira, R. Jones
11 April 2016 - P1263
WCK4282 (high-dose cefepime-tazobactam) antimicrobial activity against Gram-negative organisms from United States (USA) and Latin American medical centres (2014)
Helio S. Sader, Sader Helio, Pillar Chris, H. Sader, M. Castanheira, R. Flamm, D. Farrell, R. Jones
11 April 2016 - P1264
WCK 4282 (high-dose Cefepime-Tazobactam): Complimentary features drive efficacy against KPC-producing pathogens
Sachin Bhagwat, Pillar Chris, Bhagwat Sachin, H. Khande, J. Prashant, S. Palwe, K. Umarkar, S. Takalkar, S. Bhagwat, M. Patel
11 April 2016 - P1265
WCK 4282 (high-dose cefepime-tazobactam) against multi-resistant Gram-negative bacteria
David Livermore, Livermore David, Comella Connie, D. Livermore, S. Mushtaq, M. Warner, N. Woodford
11 April 2016 - P1266
WCK 4282 (high-dose cefepime-tazobactam) – time-kill studies correlate with in vivo efficacy studies against AmpC-producing Pseudomonas aeruginosa
Mahesh Patel, Comella Connie, Patel Mahesh, K. Umarkar, J. Satav, A. Uday, A. Kulkarni, H. Khande, S. Palwe, S. Takalkar, S. Bhagwat, M. Patel
11 April 2016 - P1245
Pharmacodynamics of Cefepime and Tazobactam against carbapenemase positive strains in a neutropenic mouse model
Johan Mouton, Mouton Johan Willem, Dubois Véronique, J. Mouton, R. Donnelly, S. Bhagwat, M. Patel
10 April 2016 - P0806
WCK 4282 (cefepime-tazobactam) MIC quality control ranges using a multi-laboratory study design
Helio S. Sader, Săndulescu Oana, Sader Helio, J. Ross, R. Flamm, R. Jones, H. Sader
09 April 2016 - EV0631
WCK 4282 (high-dose cefepime-tazobactam) extends coverage to carbapenem-resistant Klebsiella harbouring multiple ESBLs, OXA 48/181 in conjunction with impermeability
Mahesh Patel, Patel Mahesh, A. Kulkarni, S. Biniwale, J. Satav, A. Uday, S. Bhagwat, M. Patel
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