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ESCMID Global 2024
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From the archive: ECCMID and more before 2010
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11 April 2016 - P1310
TP-6076 is efficacious in a mouse pneumonia model with carbapenem-resistant Acinetobacter baumannii (CRAB) and retains potency against common tetracycline-resistance mechanisms
Trudy Grossman, Dale Glenn, Grossman Trudy, T. Grossman, C. Fyfe, K. Kerstein, X. Xiao, C. Sun, J. Newman, P. Nguyen, M. Pulse, W. Weiss, J. Dumas, J. Sutcliffe
09 April 2016 - P0265
In vitro activity of eravacycline and comparators against Acinetobacter baumannii, including carbapenem-resistant strains, and Stenotrophomonas maltophilia isolated from patients in Europe
Patrick Scoble, Scoble Patrick, Brodrick Hayley, M. Bassetti, I. Morrissey, T. Grossman, K. Luepke, P. Scoble, J. Sutcliffe
09 April 2016 - P0342
Eravacycline in vitro activity against clinical isolates obtained from urinary and gastro-intestinal sources, including drug-resistant pathogens, from patients in Europe
Hina Patel, Snyder Jessica, Patel Hina, M. Bassetti, I. Morrissey, T. Grossman, M. Olesky, H. Patel, J. Sutcliffe
09 April 2016 - P0343
In vitro activity of eravacycline and comparators in Gram-negative organisms, including drug-resistant phenotypes, isolated from respiratory sources in Europe
Hina Patel, Patel Hina, Kulikalova Elena, M. Bassetti, I. Morrissey, T. Grossman, M. Olesky, H. Patel, J. Sutcliffe
09 April 2016 - P0344
In vitro activity of eravacycline and comparators against Enterobacteriaceae, including subgroups of strains with resistance to carbapenems or 3rd/4th-generation cephalosporins, isolated from patients in Europe
Patrick Scoble, Souza Dilair, Scoble Patrick, M. Bassetti, I. Morrissey, T. Grossman, K. Luepke, P. Scoble, J. Sutcliffe
29 April 2013 - P2107
Time to defervescence as an early marker of clinical response in patients with complicated intra-abdominal infections treated with eravacycline or ertapenem
Patrick Horn, P. Horn*, J. Sutcliffe, S. Walpole (Watertown, US)
28 April 2013 - O277
Characterisation of baseline pathogens and microbiological eradication in a phase 2 trial for treatment of complicated intra-abdominal infections comparing eravacycline (TP-434) to ertapenem
Joyce Sutcliffe, C. Fyfe, J. Deane, T.H. Grossman, P. Horn, G. Moore, D. Sahm, J. Studeny, S. Walpole, J. Sutcliffe* (Watertown, Chantilly, US)
01 April 2012 - P1425
Mouse pharmacokinetics, dose fractionation and efficacy of TP-559, a novel tetracycline with anti-Pseudomonas activity, in murine infection models challenged with Pseudomonas aeruginosa
Joyce Sutcliffe, J. Sutcliffe*, X. Xiao, R. Clark, T. Grossman (Watertown, US)
01 April 2012 - P1428
TP-834, an isoindoline-containing pentacycline antibiotic, is orally bioavailable, metabolically stable and has low potential for drug-drug interactions
Trudy Grossman, T. Grossman*, M. Ronn, N. Dunwoody, J. Sutcliffe (Watertown, US)
01 April 2012 - P1452
The novel isoindoline-containing pentacycline TP-834 is active against community and biothreat respiratory pathogens, and problematic Gram-positive pathogens
Trudy Grossman, T. Grossman*, W. O'Brien, C. Fyfe, J. Sutcliffe (Watertown, US)
01 April 2012 - P1426
The intravenous pharmacokinetics and efficacy of a novel tetracycline TP-433 in murine infection models challenged with Pseudomonas aeruginosa
Joyce Sutcliffe, Y. Deng, T. Grossman, R. Clark, X. Xiao, J. Sutcliffe* (Watertown, US)
01 April 2012 - P1427
TP-834, a novel IV and oral isoindoline-containing pentacycline, is highly efficacious in rodent models of pneumonia
Trudy Grossman, J. Sutcliffe*, P. Hogan, C. Katz, W. Zhang, Z. Zhu, T. Grossman (Watertown, US)
01 April 2012 - P1451
Synthesis and antibacterial activity of isoindoline-containing pentacyclines: a novel class of tetracycline analogs with oral bioavailability
Xiaoyi Xiao, R. Clark, D. Hunt, M. He, C. Fyfe, W. O'Brien, T. Grossman, J. Sutcliffe, X. Xiao* (Watertown, US)
01 April 2012 - P1448
In vitro potency of novel tetracyclines against Pseudomonas aeruginosa and other major Gram-negative pathogens
Joyce Sutcliffe, W. O'Brien, C. Fyfe, T. Grossman, C. Chen, R. Clark, Y. Deng, M. He, D. Hunt, C. Sun, X. Xiao, J. Sutcliffe* (Watertown, US)
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