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ESCMID Global 2024
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From the archive: ECCMID and more before 2010
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30 April 2024 - O1337
Minimal inhibitory concentration of ethionamide alone and in combination with alpibectir on drug-sensitive and drug-resistant clinical isolates of Mycobacterium tuberculosis
Line Hofmann, Praha Rupasinghe, Leen Rigouts, Bouke De Jong, Karine Soetaert, Vanessa Mathys, Nicolas Willand, Modesto Remuiñán, Marc Gitzinger, Glenn Dale, Alain Baulard, Michel Pieren
28 April 2024 - P2444
Pharmacokinetics of ethionamide and ethionamide sulfoxide in patients established on treatment for tuberculosis
Michel Pieren, Pierre Delique, Lisa Husband, Marc Gitzinger, Caryn Upton, Jeantelle Du Preez, Glenn Dale
28 April 2024 - P2449
Pharmacokinetic and pharmacodynamic properties of polymyxin B in Acinetobacter baumannii murine infection models
Sanne Van Den Berg, Michel Pieren, Sebastiaan Sassen, Marian Ten Kate, Glenn Dale, Anouk Muller,
28 April 2024 - P2295
In vivo efficacy of BV100 in combination with polymyxin B (POL) in neutropenic murine thigh infection models of Acinetobacter baumannii
Michel Pieren, Sanne Van Den Berg, Mark E. Pulse, William Weiss, Jessica S.C. Boonman, Anouk Edwina Muller, Francoise Jung, Glenn Dale
28 April 2024 - P2431
BV100 displays potent efficacy against Acinetobacter baumannii in neutropenic murine thigh and lung infection models
Michel Pieren, Anouk Edwina Muller, Mark E. Pulse, William Weiss, Willem A. M. De Jong, Van Den Berg Sanne, Francoise Jung, Glenn Dale
17 April 2023 - P2188
Revisiting ethionamide in vivo activity through its metabolite exposure
Thomas Maitre, Glenn Dale, Zainab Edoo, Mohammad Al-Shaer, Anne-Grete Märtson, Caryn Upton, Céline Mory, Najoua El Helali, Aurélie Chauffour, Laure Fournier Le Ray, Alexandre Godmer, Alexandra Aubry, Aurore Dreneau, Nicolas Willand, Alain Baulard, Marc Gitzinger, Sergio Lociuro, Michel Pieren, Nicolas Veziris
23 April 2022 - P1272
In vitro activity of BV200 anti-virulent small molecules against a large and geographically diverse panel of Staphylococcus aureus isolates from skin and lung infections
Vincent Trebosc, Julian Schill, Birgit Schellhorn, Alessia Michelotti, Marc Gitzinger, Michel Pieren, Marilyne Bourotte, Glenn Dale, Olivier Defert, Sergio Lociuro
23 April 2022 - P0135
The sulfoxide metabolite of ethionamide has antibacterial activity against Mycobacterium tuberculosis and is boosted by clinical candidate BVL-GSK098
Zainab Edoo, Aurore Dreneau, Thomas Maitre, Nicolas Véziris, Olivier Defert, Glenn E. Dale, Sergio Lociuro, Marc Gitzinger, Nicolas Willand, Alain Baulard, Michel Pieren
23 April 2022 - P1260
Label-free quantitative proteomic reveals the broad anti-toxin activity of BV200 anti-virulent agents against Staphylococcus aureus.
Vincent Trebosc, Minia Antelo-Varela, Julian Schill, Alessia Michelotti, Marc Gitzinger, Glenn Dale, Marilyne Bourotte, Olivier Defert, Michel Pieren, Andrej Trauner, Alexander Schmidt, Dirk Bumann, Sergio Lociuro
15 April 2019 - O0919
Inhibition of AgrA-mediated virulence factor expression in MRSA reduced disease severity of skin and soft tissue infections 1.0.0.20 1.0.0.20
Michel Pieren, Marilyne Bourotte, Christian Kemmer, Birgit Schellhorn, Julian Schill, Vincent Trebosc, Valentina Lucchini, Marc Gitzinger, Sergio Lociuro
12 April 2016 - O585
The TRIC target evaluation platform revealed an AdeR unrelated tigecycline resistance mechanism in XDR Acinetobacter baumannii clinical isolates
Michel Pieren, Pieren Michel, V. Trebosc, S. Gartenmann, B. Schellhorn, K. Royet, P. Manfredi, M. Tigges, M. Pieren, S. Lociuro, M. Gitzinger, C. Kemmer
12 April 2016 - O526
Identification of VanR inhibitors re-sensitising vancomycin-resistant enterococci (VRE) towards glycopeptide antibiotics
Michel Pieren, Pieren Michel, B. Schellhorn, C. Kemmer, V. Lucchini, S. Gartenmann, V. Trebosc, F. Deroose, P. Sennhenn, S. Lociuro, M. Tigges, M. Gitzinger, M. Pieren
10 April 2016 - PIP01
BioVersys: Transcriptional Regulator Inhibitory Compounds (TRIC): Switches for Resistance, Virulence and Essential Genes
Sergio Lociuro, Marc Gitzinger, Birgit Schellhorn, Vincent Trebosc, Christian Kemmer, Peter Sennhen, Michel Pieren
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