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ESCMID Global 2024
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From the archive: ECCMID and more before 2010
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09 July 2021 - 4411
Setting up of a model for the study of antibiotic protein binding and prediction of interferences by other drugs: application with temocillin
Perrin Ngougni Pokem, P. Ngougni Pokem, F. Van Bambeke, P. Tulkens
24 April 2018 - P2220
Population pharmacokinetic modelling of total and unbound temocillin in the plasma of healthy volunteers after intravenous administration
Perrin Ngougni Pokem, P. Ngougni Pokem, P. Matzneller, B. Wulkersdorfer, A. Capron, l. elens, P. Wallemacq, P. Tulkens, M. Zeitlinger, F. Van Bambeke
24 April 2018 - P2219
Protein binding of temocillin is lower in plasma from patients in intensive care units compared to healthy subjects: in vitro and in vivo studies
Perrin Ngougni Pokem, P. Ngougni Pokem, P. Matzneller, B. Wulkersdorfer, A. Capron, P. Tulkens, P. Wallemacq, M. Zeitlinger, P. Laterre, J. Mouton, F. Van Bambeke
23 April 2018 - P1526
Activity of fluoroquinolones (finafloxacin, levofloxacin, ciprofloxacin) vs. that of imipenem against extracellular and intracellular forms of infection by Burkholderia thailandensis
Mariana Castanheira, H. Chalhoub, S. Harding, P. Tulkens, F. Van Bambeke
23 April 2018 - P1523
Cellular pharmacokinetics (accumulation, subcellular distribution, efflux) of the FabI inhibitor Debio 1452 in J774 macrophages
Paul M. Tulkens, A. van Wessem, F. Peyrusson, G. Dieppois, P. Tulkens, F. Van Bambeke
23 April 2018 - P1525
The putative de-N-acetylase DnpA increases intracellular and biofilm-associated persistence upon fluoroquinolone exposure in Pseudomonas aeruginosa
Onya Opota, S. Khandekar, V. Liebens, M. Fauvart, P. Tulkens, J. Michiels, F. Van Bambeke
21 April 2018 - P0146
Oxazolidinones induce mitochondrial metabolism impairment at clinically-relevant concentrations in human megakaryocytic cell lines (UT7-WT and UT7-MPL)
Francoise Van Bambeke, T. Milosevic, P. Thomas, G. Vertenoeil, V. Payen, P. Sonveaux, P. Tulkens, S. Constantinescu, F. Van Bambeke
11 April 2016 - P1334
Activity of the novel Fabl inhibitor Debio 1452 against intracellular forms of susceptible and resistant S. aureus: comparison with linezolid, vancomycin and daptomycin
Paul M. Tulkens, Tulkens Paul, Paukner Susanne, F. Peyrusson, F. Van Bambeke, P. Tulkens
10 April 2016 - O250
Achieving pharmacokinetic/pharmacodynamic (PK/PD) targets of beta-lactams in critically ill patients at first dose: can we do it with standard dosing?
Isabelle Delattre, Delattre Isabelle, I. Delattre, F. Taccone, F. Jacobs, T. Dugernier, H. Spapen, P. Laterre, P. Wallemacq, V. Tam, F. Van Bambeke, P. Tulkens
10 April 2016 - P0762
Cooperation between active efflux and porin alteration is sufficient to confer high-level resistance to meropenem (MEM) in Pseudomonas aeruginosa (Pa) clinical isolates
Françoise Van Bambeke, Perez de Ayala Balzola Ana, Van Bambeke Francoise, H. Chalhoub, Y. Saenz, H. Rodriguez-Villalobos, O. Denis, B. Kahl, P. Tulkens, F. Van Bambeke
09 April 2016 - EV0626
Cellular pharmacokinetics of gepotidacin (GSK2140944) in human THP-1 monocytes (THP-1) and murine macrophages (J774)
Paul M. Tulkens, Tulkens Paul, F. Peyrusson, F. Van Bambeke, P. Tulkens
30 April 2013 - O608
Activities of amoxicillin (AMX), clarithromycin (CLR) and moxifloxacin (MXF) towards intracellular forms of Streptococcus pneumoniae with increasing mutant inhibitory concentrations (MICs): attempt at defining an intracellular susceptibility breakpoint
Paul M. Tulkens, S. Lemaire*, M. van der Linden, F. Van Bambeke, P. Tulkens (Brussels, BE; Aachen, DE)
28 April 2013 - P1614
Dissociation of minimum inhibitory concentration (MIC) distributions of ceftaroline (CPT) and amoxicillin (AMX) in a clinical collection of Streptococcus pneumoniae from respiratory tract infection isolates with reduced susceptibility to AMX
Paul M. Tulkens, S. Lemaire*, M. van der Linden, P. Tulkens (Brussels, BE; Aachen, DE)
27 April 2013 - O175
Catalase (CAT) activity in Staphylococcus aureus (SA) is associated with increased susceptibility to hydrogen peroxide killing and to decreased intracellular growth
Paul M. Tulkens, S. Lemaire*, R. Leclercq, B. Kahl, F. Van Bambeke, P. Tulkens (Brussels, BE; Caen, FR; Münster, DE)
03 April 2012 - P2210
Clinical safety of moxifloxacin: an analysis of "Valid for Safety" data from controlled phase II to phase IV studies performed between 1996 and 2010
Paul M. Tulkens, P. Tulkens*, P. Arvis, F. Kruesmann (Brussels, BE; Loos, FR; Wuppertal, DE)
01 April 2012 - P1602
Pharmacodynamic analysis of the susceptibility of intracellular methicillin-susceptible, methicillin-resistant and linezolid-resistant Staphylococcus aureus to ceftaroline
Paul M. Tulkens, A. Melard, S. Lemaire*, P. Tulkens, F. Van Bambeke (Brussels, BE)
01 April 2012 - P1279
Fluoroquinolone recognition by prokaryotic S. aureus NorA and eukaryotic murine Mrp4 efflux transporters: a combined experimental and structural study
Paul M. Tulkens, J. Dupont, C. Vallet, P. Tulkens*, M. Prévost, F. Van Bambeke (Brussels, BE)
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