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ECCMID 2023
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From the archive: ECCMID and more before 2010
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27 April 2013 - P914
Pharmacokinetic-pharmacodynamics (PK-PD) predict a high probability of efficacy for plazomicin against serious infections caused by carbapenem-resistant Enterobacteriaceae (CRE)
Sujata M. Bhavnani, S.A. Van Wart, A. Forrest, G.L. Drusano, S.M. Bhavnani*, C.C. Bulik, C.F. Kostrub, P.G. Ambrose, A. Louie (Latham, Orlando, South San Francisco, US)
27 April 2013 - P915
Use of pharmacokinetics-pharmacodynamics (PK-PD) and Monte Carlo simulation (MCS) analyses to support brilacidin (BRI) dose selection for patients with acute bacterial skin and skin structure infections (ABSSSI)
Sujata M. Bhavnani, S.M. Bhavnani*, J.P. Hammel, A. Forrest, M. Melhem, P. Sager, K.J. Tack, P.G. Ambrose, D.M. Jorgensen (Latham, San Francisco, Brighton, Radnor, US)
27 April 2013 - P916
Pharmacokinetic-pharmacodynamic (PK-PD) analyses for efficacy and safety of brilacidin (BRI) using data from patients with acute bacterial skin and skin structure infections (ABSSSI)
Sujata M. Bhavnani, S.M. Bhavnani*, J.P. Hammel, A. Forrest, M. Melhem, P. Sager, D.M. Jorgensen, P.G. Ambrose (Latham, San Francisco, Radnor, US)
27 April 2013 - P917
Population pharmacokinetic (PPK) analyses of brilacidin using data from healthy subjects and patients with acute bacterial skin and skin structure infections (ABSSSI)
Sujata M. Bhavnani, M. Melhem, C.M. Rubino, S.M. Bhavnani, A. Forrest*, D.K. Reynolds, D.M. Jorgensen, B. Korczak, P.G. Ambrose (Latham, Radnor, US)
27 April 2013 - P918
The pharmacokinetics (PK) and safety of plazomicin in subjects with renal impairment
Todd Clobes, V. Riddle, D. Cebrik, C. Kostrub, L. Ma*, K. Hillan (Crofton, San Francisco, South San Francisco, US)
27 April 2013 - P919
The effect of food and formulation on the pharmacokinetics of GSK1322322 in healthy subjects
Odin Naderer, O.J. Naderer*, L.S. Jones, J.Z. Zhu, M.D. Coffin, M.T. Kurtinecz, E.F. Dumont (Research Triangle Park, Upper Merion, Upper Providence, US)
27 April 2013 - P920
Pharmacokinetics/pharmacodynamics (PK/PD) of peptide deformylase inhibitor GSK1322322 against Staphylococcus aureus in a rat abscess model
Thomas Lewandowski, T. Lewandowski*, J. Hoover, S. Rittenhouse (Collegeville, US)
27 April 2013 - P921
Lack of pharmacokinetic drug interaction of tedizolid phosphate with pseudoephedrine in healthy subjects
Johnna Simoes, S. Flanagan*, S. Minassian, K.A. Munõz, H. Dreskin, E. Fang, P. Prokocimer (San Diego, US)
27 April 2013 - P922
Dialysability of antiinfective drugs: an in vitro model with continuous haemodialysis
Otto Roman Frey, A.C. Röhr*, O.R. Frey, A. Köberer, T. Fuchs, J.A. Preisenberger, S.L. Helbig, A. Brinkmann (Heidenheim, DE)
27 April 2013 - P923
Micafungin pharmacokinetics during continuous venovenous haemofiltration in critically ill patients
Emilio Maseda, E. Maseda*, S. Grau, M.-J. Villagran, C. Hernandez-Gancedo, A. Lopez-Tofiño, L. Aguilar, S. Luque, F. Gilsanz (Madrid, Barcelona, ES)
27 April 2013 - P924
Cerebrospinal fluid concentration of ceftazidime administered by continuous infusion at high dose in ventriculitis associated with external ventricular drainage
Patricio Mas-Serrano, P. Más-Serrano*, J.A. Navarro-Martinez, C. Pastor-Cerdan, C. Ferrero, F. Martinez-Adsuar, E. Climent, I. Gascon, E. Merino, G. Riera, R. Nalda-Molina, A. Ramon-Lopez, R. Company-Teuler, J. Selva (Alicante, Benidorm, Elche, ES)
27 April 2013 - P925
Target attainment rates (TAR) and cumulative fraction of response (CFR) in plasma for ceftolozane in a simulated population of patients with complicated intra-abdominal (cIAI) and urinary tract infection (cUTI)
Gurudatt Chandorkar, G Chandorkar*, J. Steenbergen, S. Mouksassi, D. Benziger (Lexington, US; Quebec, CA)
27 April 2013 - P926
DALI: defining antibiotic levels in intensive care unit patient. Variability of protein binding of teicoplanin and achievement of TDM targets
Jason Roberts, J. Roberts*, M. Bassetti, J. Dewaele, G. Dimopoulos, D. Koulenti, C. Martin, B. McWhinney, P. Montravers, S. Parker-Scott, J. Rello, A. Rhodes, B. Sipinkoski, T. Starr, V. Stove, J. Ungerer, S. Wallis, J. Lipman (Brisbane, AU; Genova, IT; Ghent, BE; Athens, GR; Marseille, FR; Paris, FR; Barcelona, ES; London, UK)
27 April 2013 - P927
Population pharmacokinetics of linezolid in diabetic patients with soft tissue infections: are standard doses adequate?
Iris K. Minichmayr, I.K. Minichmayr*, A. Schaeftlein, M. Zeitlinger, C. Kloft (Berlin, DE; Vienna, AT)
27 April 2013 - P928
Population pharmacokinetics of amikacine in ventilator-associated pneumonia
Charles Burdet, C. Burdet*, O. Pajot, C. Couffignal, L. Massias, L. Armand-Lefèvre, A. Foucrier, C. Laouénan, M. Wolff, F. Mentré (Paris, FR)
27 April 2013 - P929
Fluoroquinolone resistance in Escherichia coli: search for the optimal predictor using in vitro dynamic models
Alexander Firsov, E. Strukova, D. Shlykova, Y. Portnoy, S. Zinner, A. Firsov* (Moscow, RU; Cambridge, US)
27 April 2013 - P930
Pharmacodynamic interactions of tigecycline and colistin combination against Pseudomonas aeruginosa using microdilution checkerboard and time-kill method
Sophia Vourli, S. Vourli*, J. Meletiadis, T. Karonis, N. Siafakas, L. Zerva (Athens, GR)
27 April 2013 - P931
Whole-body physiologically-based pharmacokinetic model for colistin and colistimethate sodium (CMS) in five different animal species: mouse, rat, rabbit, baboon and pig
Salim Bouchene, S. Bouchene*, S. Marchand, L.E. Friberg, S. Björkman, W. Couet, M.O. Karlsson (Uppsala, SE; Poitiers, FR)
27 April 2013 - P932
Polymyxin B induces DNA breakage and mitochondrial morphology changes in rat kidney tubular cells
Mohammad Azad, M.A.K. Azad*, L. Whitehead, C. Nowell, K. Rogers, R.L. Nation, T. Velkov, J. Li (Melbourne, AU)
27 April 2013 - P933
Characterisation of semi-mechanistic pharmacokinetic-pharmacodynamic models of antibacterial activity via Monte Carlo simulations
Matthieu Jacobs, M. Jacobs*, N. Gregoire, W. Couet, J. Bulitta (Poitiers, FR; Melbourne, AU)
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