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ESCMID Global 2024
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Guidelines
From the archive: ECCMID and more before 2010
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13 May 2014 - P1727
Penetration of colistin into central nervous system in critically ill patients with proven or suspected central nervous system infections
Sonia Luque, Luque, S.(1)*; Sorli, L.(2); Alvarez-Lerma, F.(3); Campillo, N.(1); Basas, M.(3); Horcajada, J.P.(2); Knobel, H.(2); Montero, M.(2); Salas, E.(1); Grau, S.(1);
13 May 2014 - P1728
Pharmacokinetics of colistin methanesulfonate (CMS) in burns patients
Lorena Baietto, Baietto, L.(1)*; D'Avolio, A.(1); Corcione, S.(1); Malvasio, V.(2); Di Perri, G.(1); Stella, M.(2); De Rosa, F.G.(1);
13 May 2014 - P1729
Tissue exposure kinetics of colistin sulfate in a neutropenic mouse thigh model
Renu Singh, Singh, R.(1)*; Farrington, K.(1); Sathe, A.(2); Gupta, A.(2); Hale, M.(3); Kern, G.(1);
13 May 2014 - P1730
Polymyxin B: can we create a better product?
Zahra Kassamali, Kassamali, Z.(1)*; Rhomberg, P.R.(2); Jones, R.N.(3); Danziger, L.H.(4); Prince, R.A.(5);
13 May 2014 - P1731
Methionine ameliorates polymyxin-induced nephrotoxicity in mice
Jian Li, Wang, J.(1); Azad, M.A.K.(1); Nation, R.L.(1); Roberts, K.D.(2); Thompson, P.E.(2); Velkov, T.(1); Li, J.(1)*;
13 May 2014 - P1732
Predictors of fluoroquinolone resistance in Pseudomonas aeruginosa: area under the curve related to either MIC or the mutant prevention concentration
Alexander A. Firsov, Strukova, E.(1)*; Shlykova, D.(1); Portnoy, Y.(1); Zinner, S.(2); Firsov, A.(1);
13 May 2014 - P1733
Use of cefepime against P. aeruginosa in a murine pneumonia model
George Drusano, Drusano, G.(1)*; Liu, W.(1); Fikes, S.(1); Robbins, N.(1); Kurhanewicz, S.(1); Rodriguez, J.(1); Baluya, D.(1); Louie, A.(1);
13 May 2014 - P1734
Post-antibiotic effect (PAE) and post-beta-lactamase-inhibitor effect (PLIE) of ceftazidime, ceftaroline and aztreonam, alone and in combination with avibactam against target Gram-negative organisms with extended-spectrum beta-lactamases
Chris Pillar, Pillar, C.M.(1)*; Stoneburner, A.(1); Shinabarger, D.L.(1); Krause, K.(2); Nichols, W.W.(3);
13 May 2014 - P1735
In vivo pharmacodynamics of ceftolozane against Streptococcus pneumoniae and Pseudomonas aeruginosa across a wide range of MICs in a neutropenic murine thigh infection model
David Andes, Andes, D.(1)*; Alex, L.(1);
13 May 2014 - P1736
Pharmacodynamics of tazobactam combined with cefepime in a neutropenic mouse thigh model
Ria Melchers, Melchers, M.J.(1)*; van Mil, A.C.(1); Lagarde, C.(1); Mouton, J.W.(1);
13 May 2014 - P1737
Phase I, randomised single- and multiple-dose study of ceftaroline fosamil 600 mg every 12 h (60-min infusion) and every 8 h (120-min infusion)
Mark Waterlow, Sunzel, M.(1)*; Kujacic, M.(2); Broadhurst, H.(3); Li, J.(1); Edeki, T.(1);
13 May 2014 - P1738
Pharmacodynamic profiling of intravenous beta-lactams against Gram-negative isolates from bloodstream infections from a Brazilian hospital
Leandro Cardinal, Cardinal, L.S.M.(1)*; Macedo, R.S.(1); Cabral, L.G.(1); Meneses, J.P.(1); Monteiro, V.G.(2); Neto, P.A.M.(3); Araújo, M.R.E.(3); Duarte, A.S.(3); Furtado, G.H.(2);
13 May 2014 - P1739
In treatment of Pseudomonas aeruginosa with piperacillin tazobactam, addition of low dose gentamicin markedly reduces emergence of resistance and increases antibacterial effect
Alexandra Cochrane, Cochrane, A.(1)*; Bowker, K.(2); Noel, A.(2); MacGowan, A.(2);
13 May 2014 - P1740
Exploring PK/PD relationship of a novel beta-lactamase inhibitor MK-7655 in combination with imipenem in a hollow fibre infection model
Jin Wu, Wu, J.(1)*; Racine, F.(2); Rizk, M.L.(3); Wismer, M.K.(4); Harradine, P.(5); Young, K.(2); Motyl, M.(2);
13 May 2014 - P1741
Protein binding of ertapenem in plasma from healthy volunteers and from ICU patients
Frieder Kees, Kratzer, A.(1); Liebchen, U.(2); Wicha, S.G.(3); Kees, F.(4)*; Kees, M.G.(5);
13 May 2014 - P1742
Population pharmacokinetic and pharmacodynamic analysis of metronidazole in Japanese patients with intra-abdominal infections and pelvic inflammatory disease
Nobuko Takenaka, Takenaka, N.(1)*; Shoji, S.(1); Tomono, Y.(1);
13 May 2014 - P1743
Pharmacokinetic-pharmacodynamic (PK-PD) target attainment (TA) analyses supporting the selection of in vitro susceptibility test interpretive criteria for ceftolozane/tazobactam (TOL/TAZ) against Pseudomonas aeruginosa
Paul Ambrose, Melhem, M.(1); Forrest, A.(1); Rubino, C.(1); Bhavnani, S.(1); Steenbergen, J.(2); Krishna, G.(2); Ambrose, P.(1)*;
13 May 2014 - P1744
Monte Carlo simulation to evaluate the probability of attaining targeted pharmacodynamic exposure of ceftaroline fosamil against pathogens associated with CAP and SSTI in Europe
Alicia Rodríguez-Gascón, Rodríguez-Gascón, A.(1)*; Isla, A.(1); Canut, A.(2);
13 May 2014 - P1745
Pharmacokinetic/pharmacodynamic analysis of moxifloxacin in patients with diabetic foot infections
Sebastian Wicha, Wicha, S.G.(1)*; Zink, K.(2); Haak, T(2); Kees, F.(3); Kloft, C.(1); Kees, M.G.(4);
13 May 2014 - P1746
Use of Bayesian pharmacokinetic models to predict meropenem concentrations in critically ill patients – application to therapeutic drug monitoring
Andras Farkas, Farkas, A.(1); Wong, G.(2); Daroczi, G.(3); Lipman, J.(2); Roberts, J.(2)*;
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