Aubin Souche, Pierre Chauvelot, Camille Kolenda, Raymond Schuch, Florent Valour, Tristan Ferry, Frederic Laurent, , Jérôme Josse
Poster Session
ESCMID Global 2024
Courses & Events
Guidelines
From the archive: ECCMID and more before 2010
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28 April 2024
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P2278
Lysin exebacase demonstrates potent bactericidal activity against intraosteoblastic Staphylococcus aureus
17 April 2023
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P2120
Activity of lysin CF-370 at the cell envelope of Gram-negative (GN) ESKAPE pathogens revealed by electron microscopy
17 April 2023
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P2175
Lysin exebacase exerts potent in vitro bactericidal activity against Staphylococcus aureus strains associated with pulmonary exacerbations (PExs) of cystic fibrosis (CF)
Jun Oh, Matthew Warner, Aubrey Watson, Xavier Vila-Farres, Jane Ambler, Cara Cassino, Raymond Schuch
Poster Session
17 April 2023
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P2141
Bacteriolytic and anti-virulence activities of engineered lysin CF-370 against Gram-negative (GN) ESKAPE pathogens
Juliana Da Costa Ramos, Xavier Vila-Farres, Karen Sauve, Aubrey Watson, Steven Swift, Raymond Schuch
Poster Session
15 April 2023
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E0112
Efficacy of lysin CF-370 in addition to amikacin in a neutropenic rabbit lung infection model caused by an extensively drug-resistant (XDR) P. aeruginosa
26 April 2022
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O0819
In vivo efficacy of CF-370 alone and in addition to amikacin in the rabbit acute pneumonia model caused by an extensively drug-resistant (XDR) Pseudomonas aeruginosa, AR-769
23 April 2022
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P1294
Lysin CF-370 suppresses in vitro resistance in Pseudomonas aeruginosa to meropenem, tobramycin and levofloxacin
23 April 2022
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P1296
Lysin CF-370 exhibits a low propensity for decreased susceptibility in Gram-negative (GN) ESKAPE pathogens
23 April 2022
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P1295
Direct lytic agents, a novel family of antmicrobial agents, have a low propensity for decreased susceptibility in Gram-negative pathogens associated with airway infection in cystic fibrosis
23 April 2022
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P0496
In vitro activity of exebacase against contemporary beta-haemolytic streptococci recovered from US patients with bloodstream infections
16 April 2019
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L0012
Exebacase (Lysin CF-301) improved clinical responder rates in methicillin resistant Staphylococcus aureus bacteremia including endocarditis compared to standard of care antibiotics alone in a first-in patient Phase 2 study
13 April 2019
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P0528
Lysin exebacase (CF-301) exhibits potent bactericidal activity in human synovial fluid against biofilm-forming Staphylococcus epidermidis isolates
13 April 2019
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O0200
Lysin GN123 resensitizes carbapenem-resistant Pseudomonas aeruginosa to imipenem
24 April 2018
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P2450
European surveillance study of CF-301 activity against contemporary Staphylococcus aureus isolates from Italy, Greece, and Hungary
24 April 2018
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P2452
Lysin CF-301 exhibits a low propensity for decreased susceptibility and prevents daptomycin (DAP) resistance in a rabbit model of S. aureus infective endocarditis (IE)
22 April 2018
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O0581
Efficacy of lysin CF-301 in addition to daptomycin (DAP) or vancomycin (VAN) in a rabbit model of infective endocarditis (IE) due to methicillin-resistant Staphylococcus aureus (MRSA)
22 April 2017
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EV0038
Development of an antimicrobial susceptibility test (AST) for the antistaphylococcal lysin CF-301
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