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From the archive: ECCMID and more before 2010
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29 April 2024 - P2973
Front-loaded exposures increase the fungicidal effect of SF001: a basis for infrequent dosing regimens
Brian Vanscoy, Steven Fikes, Haley Conde, Sujata Bhavnani, Christopher Rubino, Paul Ambrose
29 April 2024 - P1559
Identification of in vitro susceptibility test interpretive criteria (STIC) for sulfamethoxazole (SMX)-trimethoprim (TMP) against Escherichia coli and Klebsiella pneumoniae
Brian Vanscoy, Christopher Rubino, Sujata Bhavnani, Jeffrey Hammel, Haley Conde, Kyle Lamora, Helio Sader, M. Courtney Safir, Mariana Castanheira, Paul Ambrose
28 April 2024 - E0551
Evaluation of ANT3310 pharmacokinetics-pharmacodynamics, in combination with meropenem, using a dynamic In vitro infection model
Brian Vanscoy, Haley Conde, Catherine Vincent, Christopher Rubino, Sujata Bhavnani, Magdalena Zalacain, Agustina Llanos, Adeline Ledoux, Paul Ambrose
28 April 2024 - E0556
Identification of azithromycin and ceftriaxone In vitro susceptibility test interpretive criteria (STIC) for Neisseria gonorrhoeae
Sujata Bhavnani, Brian Vanscoy, Jeffrey Hammel, Christopher Rubino, Haley Conde, M. Courtney Safir, Xiaoyu Wang, Helio Sader, Rodrigo Mendes, Paul Ambrose
17 April 2023 - P2197
In vivo PK/PD characterization of a novel polyene SF001 in the invasive pulmonary aspergillosis (IPA) mouse model
Alexander Lepak, Brian Vanscoy, Chris Rubino, Paul Ambrose, David Andes
24 April 2022 - O0301
Development of modernised Acinetobacter baumannii susceptibility guidance for recommended antimicrobial agents using pharmacometric approaches
Alexander Lepak, Brian Vanscoy, Helio Sader, Michael Trang, Jeffrey Hammel, Sujata Bhavnani, Paul Ambrose, David Andes
23 April 2022 - O0115
In vivo pharmacodynamic evaluation of meropenem-nacubactam in murine thigh and lung infection models against Klebsiella pneumoniae (KPN) containing OXA-48-like enzymes
Alexander Lepak, Brian Vanscoy, Helio Sader, Paul Ambrose, David Andes
09 July 2021 - 388
Determination of nacubactam exposure, in combination with cefepime, required to prevent the emergence of on-therapy resistance utilising an in vitro hollow-fibre infection model
Brian D. Vanscoy, B.D. Vanscoy (1), A. Mullarkey (1), H. Conde (1), C. Balnis (1), S.M. Bhavnani (1), Y. Nagira (2), K. Asai (2), K. Kondo (2), P.G. Ambrose (1)
09 July 2021 - 387
Characterization of nacubactam pharmacokinetics-pharmacodynamics (PK-PD) for efficacy in combination with cefepime against carbapenemase-producing Enterobacterales in a one-compartment in vitro infection model
Brian D. Vanscoy, B.D. Vanscoy (1), A. Mullarkey (1), H. Conde (1), A. Caranco (1), C.M. Rubino (1), S.M. Bhavnani (1), Y. Nagira (2), K. Asai (2), K. Kondo (2), P.G. Ambrose (1)
09 July 2021 - 386
Determination of nacubactam exposure, in combination with aztreonam, required to prevent the emergence of on-therapy resistance utilising an in vitro hollow-fibre infection model
Brian D. Vanscoy, B.D. Vanscoy (1), A. Mullarkey (1), H. Conde (1), C. Balnis (1), S. Jones (1), S.M. Bhavnani (1), Y. Nagira (2), K. Asai (2), K. Kondo (2), P.G. Ambrose (1)
09 July 2021 - 385
Characterisation of nacubactam pharmacokinetics-pharmacodynamics (PK-PD) for efficacy in combination with aztreonam against carbapenemase-producing Enterobacterales in a one compartment in vitro infection model
Brian D. Vanscoy, B.D. Vanscoy (1), A. Mullarkey (1), H. Conde (1), S. Jones (1), C.M. Rubino (1), S.M. Bhavnani (1), Y. Nagira (2), K. Asai (2), K. Kondo (2), P.G. Ambrose (1)
09 July 2021 - 384
Pharmacokinetic-pharmacodynamic target attainment analyses to support dose selection for nacubactam in combination with cefepime
Sujata M. Bhavnani, S.M. Bhavnani (1), M. Trang (1), J.P. Hammel (1), N. Sato (2), B.D. Vanscoy (1), Y. Nagira (2), K. Kato (2), K. Kondo (2), P.G. Ambrose (1)
09 July 2021 - 379
Pharmacokinetic-pharmacodynamic target attainment analyses to support dose selection for nacubactam in combination with aztreonam
Sujata M. Bhavnani, S.M. Bhavnani (1), M. Trang (1), J.P. Hammel (1), N. Sato (2), B.D. Vanscoy (1), Y. Nagira (2), K. Kato (2), K. Kondo (2), P.G. Ambrose (1)
16 April 2019 - O1060
Pharmacokinetics-pharmacodynamics of the novel beta-lactamase inhibitor GT-055 in combination with the siderophore cephalosporin GT-1
Sujata M. Bhavnani, Brian D. VanScoy, Michael Trang, Haley Conde, Donald Biek, Brendan Hannah, Dirk Thye, Paul G. Ambrose
23 April 2018 - O0797
Pharmacokinetics/pharmacodynamics (PK/PD) of the novel, first-in-class glycosylphosphatidylinositol (GPI) Inhibitor APX001 in the neutropenic murine invasive candidiasis model against C. albicans (CA), C. glabrata (CG), and C. auris (CAU)
Alex Lepak, A. Lepak, M. Zhao, B. VanScoy, J. Bader, P. Ambrose, D. Andes
23 April 2018 - P1537
Pharmacokinetics-pharmacodynamics (PK-PD) of VNRX-5133, a broad-spectrum novel beta-lactamase inhibitor (BS-BLI), in combination with cefepime in a one-compartment in vitro infection model
Celia Cardozo, B. VanScoy, J. McCauley, E. Lakota, H. Conde, S. Bhavnani, T. Henkel, l. xerri, D. Pevear, P. Ambrose
22 April 2018 - P1035
Pharmacokinetic and pharmacodynamics of nacubactam in combination with meropenem in a one-compartment PK-PD in vitro infection model
Paul G. Ambrose, B. VanScoy, C. Bissantz, A. Haldimann, I. Najera, P. Ravva, E. Winter, C. Zampaloni, P. Ambrose
21 April 2018 - P0267
Evaluation of the Pharmacokinetics-Pharmacodynamics (PK/PD) indices of ME1100 (arbekacin inhalation solution) against Pseudomonas aeruginosa in a murine lung infection model
Yu Nagira, Y. Nagira, S. Ouchi, H. Okade, T. Ida, K. Kondo, B. VanScoy, P. Ambrose
06 September 2017
Relationship Between Gepotidacin (GSK1440944) Pharmacokinetics-Pharmacodynamics and Escherichia coli Resistance Amplification Prevention in a Hollow-Fiber Infection Model (HFIM)
Brian VanScoy
25 April 2015 - P0246
Relationship between arbekacin exposure and resistance amplification in a hollow-fibre infection model
Sujata M. Bhavnani, VanScoy, Brian *; McCauley, Jennifer; Conde, Haley; Baba, N; Ouchi, S; Bhavnani, Sujata; Ambrose, Paul G.;
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