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ESCMID Global 2024
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From the archive: ECCMID and more before 2010
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17 September 2024 - EA053
A Murine Pneumonia Model with Colistin Resistant and Carbapenem Resistant Acinetobacter Baumannii to Evaluate Treatments for AMR Lung Infections
Carina Matias, Jon Ulf Hansen, Carina Vingsbo Lundberg
17 September 2024 - EA036
Novel Broad-Spectrum β-Lactamase Inhibitor APC247 Restores Efficacy of Meropenem Against Carbapenem-Resistant Enterobacteriaceae in-vivo
Jon Ulf Hansen, Carina Matias, Ragnar Hovland, Pål Rongved, Carina Vingsbo Lundberg
28 April 2024 - P2289
APC148-avibactam restores meropenem susceptibility in multi-drug resistant Gram-negative bacteria in vitro
Carina Matias, Ragnar Hovland, Pål Rongved, Carina Vingsbo Lundberg, Jon Ulf Hansen
28 April 2024 - P2497
Model-informed drug development for antimicrobials: translational pharmacokinetic-pharmacodynamic modelling of apramycin to facilitate prediction of efficacious dose in complicated urinary tract infections
Irene Hernández-Lozano, Vincent Aranzana-Climent, Sha Cao, Carina Matias, Jon Ulf Hansen, Edgars Liepinsh, Diarmaid Hughes, Sven Hobbie, Carina Vingsbo Lundberg, Lena Friberg
28 April 2024 - E0759
New antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria
Douglas L. Huseby, Sha Cao, Edouard Zamaratski, Sanjeewani Sooriyaarachchi, Shabbir Ahmad, Terese Bergfors, Laura Krasnova, Juris Pelss, Martins Ikaunieks, Einars Loza, Katkevics Katkevics, Olga Bobileva, Helena Cirule, Baiba Gukalova, Solveiga Grinberga, Maria Backlund, Ivailo Simoff, Anna Leber, Talía Berruga-Fernández, Dmitry Antonov, Vivekananda Konda, Stefan Lindström, Gustav Olanders, Peter Brandt, Pawel Baranczewski, Carina Vingsbo Lundberg, Edgars Liepinsh, Edgars Suna, T. Alwyn Jones, Sherry Mowbray, Diarmaid Hughes, Anders Karlén
17 April 2023 - P2119
APC247: a novel broad spectrum β-lactamase inhibitor demonstrating efficacy in vitro and in vivo
Carina Matias, Åsmund Kaupang, Geir-Kildahl Andersen, Pål Rongved, Carina Vingsbo Lundberg, Jon Ulf Hansen
17 April 2023 - P2149
Susceptibility of blood-culture isolates to apramycin and in vivo efficacy against nine Escherichia coli and Klebsiella pneumoniae isolates in a mouse peritonitis model
Niels Frimodt-Møller, Stine Radmer Almind, Michel Plattner, Klara Haldimann, Marina Gysin, Lea Ganz, Douglas L. Huseby, Diarmaid Hughes, Jon Ulf Hansen, Carina Vingsbo Lundberg, Sven N. Hobbie
23 April 2022 - P1319
A precision antisense PNA-diaminobutanoic acid dendron conjugate with antimicrobial activity against multidrug-resistant E. coli in the murine peritonitis/sepsis model
Carina Matias, Mirko Iubatti, Isabel Maicas Gabas, Lina M. Cavaco, Elnaz Harifi Mood, Niloofar Yavari, Camilla Brolin, Carina Vingsbo-Lundberg, Peter E. Nielsen
12 July 2021 - 1846
An integrated model of plasma and lung PK and in vitro and in vivo efficacy for translational evaluation of apramycin in Pseudomonas aeruginosa lung infection
Vincent Aranzana-Climent, V. Aranzana-Climent (1), C. Vingsbo-Lundberg (2), S. Cao (3), D. Hughes (3), J. Lindberg (4), B. Platzack (4), R. Palma Villar (4), A.K. Sternbeck (4), A. Manninen (4), K. Becker (5), S. Hobbie (5), L. Friberg (1)
15 April 2019 - O0824
Translational pharmacokinetic and pharmacokinetic/pharmacodynamic modelling of preclinical in-vitro and in-vivo studies to predict the efficacious human dose of apramycin
Tomas Sou, Edgars Liepiņš, Jon Hansen, Solveiga Grinberga, Maria Backlund, Onur Ercan, Anna Petersson, Diarmaid Hughes, Magdalena Tomczak, Małgorzata Urbaś, Dorota Zabicka, Carina Vingsbo Lundberg, Sven Hobbie, Lena Friberg
23 April 2018 - P1666
Outer mebrane protein targeting antibiotics (OMPTAs): a novel class with potent in vitro and in vivo activity against E. coli-harbouring mcr-1 and/or mcr-3 genes
Glenn Dale, G. Dale, J. Teague, C. Vingsbo Lundberg, A. Luther, F. Bernardini, D. Obrecht
25 April 2017 - OS1019
Pharmacokinetics and pharmacodynamics of murepavadin (POL7080) in neutropenic lung infection models
Glenn E. Dale, Johan Mouton, M.j Melchers, Joanne Teague, Pia Thommes, Peter Warn, Jon Hansen, Carina Vingsbo Lundberg, Francesca Bernardini, Daniel Obrecht, Glenn Dale
24 April 2017 - P1367
POL7001 is highly efficacious in the murine neutropenic lung infection model
Glenn E. Dale, Glenn Dale, Joanne Teague, Pia Thommes, Peter Warn, Jon Hansen, Carina Vingsbo Lundberg, Francesca Bernardini, Daniel Obrecht
11 April 2016 - P1276
ATx201: a novel antibiotic for treatment of skin infections caused by multidrug-resistant bacteria
Morten Sommer, Koumaki Vasiliki, Sommer Morten, P. Li, J. Hansen, T. Pires dos Santos, E. Delavenne, P. Priemel, B. Jana, H. Mørck Nielsen, L. Guardabassi, C. Vingsbo Lundberg, M. Sommer
25 April 2015 - EV0296
Antibiotic treatment of carbapenem-resistant Klebsiella pneumoniae (ST258) in murine experimental infection models
Carina Vingsbo Lundberg, Vingsbo Lundberg, Carina *; Mark Andersen, Jytte; Hansen, Jon;
10 May 2014 - P0302
POL7080 is highly efficacious in the murine pneumonia model
Glenn E. Dale, Vingsbo Lundberg, C.(1); Bernardini, F.(2); Dembowsky, K.(2); Dale, G.(2)*;
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