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ESCMID Global 2024
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From the archive: ECCMID and more before 2010
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17 April 2023 - P2222
Periplasmic target site penetration rates of four β-lactamase inhibitors in Klebsiella pneumoniae carbapenemase-2 (KPC-2)-producing Klebsiella pneumoniae
Yongzhen Zhang, Yinzhi Lang, Jieqiang Zhou, Xun Tao, Alaa R. M. Sayed, Eunjeong Shin, Carolin Werkman, Nicholas M Smith, Brian T. Tsuji, Jürgen B. Bulitta
17 April 2023 - P2224
Model-informed exposure response analyses for ceftazidime and levofloxacin against Klebsiella pneumoniae and Pseudomonas aeruginosa in murine thigh infection models
Yuanyuan Jiao, Kun-Yuan Lin, Dhruvitkumar S Sutaria, Ju-Hsin Chia, Deborah Nicole Griffith, Chin-Wei Chiang, Yu-Chuan Yeh, Jui-Che Chien, Nirav R Shah, Xun Tao, Lynn Miesel, Jürgen B. Bulitta
17 April 2023 - P2182
Synergistic penicillin-binding protein (PBP) occupancy patterns in Klebsiella pneumoniae (KP) prospectively validated in a dynamic In vitro hollow fiber infection model
Eunjeong Shin, Alaa R. M. Sayed, Yinzhi Lang, Jieqiang Zhou, Jeremiah L. Oyer, Bartolome Moya, Abeer A.S. Elsayed, Dhruvitkumar S. Sutaria, Nirav R. Shah, Carolin Werkman, Rossie H. Jimenez-Nieves, Keisha C. Cadet, Xun Tao, Yuanyuan Jiao, Alicja J. Copik, Robert A. Bonomo, Herbert P. Schweizer, Richard E. Lee, John D. Boyce, Arnold Louie, Brian T. Tsuji, Afonso L. Barth, Alexandre P. Zavascki, George L. Drusano, Jürgen B. Bulitta
15 April 2023 - E0111
Synergistic killing of Acinetobacter baumannii (AB) elicited by simultaneous inactivation of three or all four penicillin-binding proteins (PBPs) among PBP1a, 1b, 2 and 3
Carolin Werkman, Nirav Shah, Marianne Megroz, Jeremiah Oyer, Deanna Deveson Lucas, Bartolome Moya Cañellas, Alaa Sayed, Abeer Elsayed, Amy Wright, Dhruvitkumar Sutaria, Xun Tao, Yinzhi Lang, Jieqiang Zhou, Eunjeong Shin, Cornelia Landersdorfer, Rossie Jimenez-Nieves, Keisha Cadet, Yuanyuan Jiao, Alicja Copik, Robert Bonomo, Arnold Louie, George Drusano, John Boyce, Jürgen Bulitta
23 April 2022 - P1262
Simultaneously inactivating three or all four penicillin-binding proteins (PBPs) among PBP1a, 1b, 2 and 3 synergistically kills Acinetobacter baumannii (AB)
Carolin Werkman, Nirav Shah, Deanna Deveson Lucas, Jeremiah Oyer, Marianne Megroz, Bartolome Moya, Alaa Sayed, Abeer Elsayed, Amy Wright, Dhruvitkumar Sutaria, Xun Tao, Yinzhi Lang, Jieqiang Zhou, Eunjeong Shin, Cornelia Landersdorfer, Rossie Jimenez-Nieves, Keisha Cadet, Yuanyuan Jiao, Alicja Copik, Robert Bonomo, Arnold Louie, George Drusano, John Boyce, Jürgen Bulitta
23 April 2022 - O0117
Synergistic penicillin-binding protein (PBP) occupancy patterns against Klebsiella pneumoniae (KP) characterised via confocal microscopy, flow cytometry, and quantitative systems pharmacology
Eunjeong Shin, Alaa R. M. Sayed, Yinzhi Lang, Jieqiang Zhou, Jeremiah L. Oyer, Bartolome Moya, Abeer A.s Elsayed, Dhruvitkumar S. Sutaria, Nirav R. Shah, Carolin Werkman, Rossie H. Jimenez-Nieves, Keisha C. Cadet, Xun Tao, Yuanyuan Jiao, Alicja J. Copik, Robert A. Bonomo, Herbert P. Schweizer, Richard E. Lee, John D. Boyce, Arnold Louie, Brian T. Tsuji, George L. Drusano, Jürgen B. Bulitta
15 April 2019 - P1948
First simultaneous population pharmacokinetic characterisation of a beta-lactam/beta-lactamase inhibitor combination: gastrointestinal transit and absorption kinetics of amoxicillin/clavulanic acid
Jürgen Bulitta, Martina Kinzig, Yuanyuan Jiao, Xun Tao, Rainer Höhl, Fritz Sorgel
15 April 2019 - P1834
Comprehensive thermal stability data and optimal supplement dosing schemes for in vitro time-kill experiments with 10 beta-lactams and 3 beta-lactamase inhibitor in Mueller-Hinton broth
Jürgen Bulitta, Yuli Qian, Xun Tao, Tae Hwan Kim, Jieqiang Zhou, Yinzhi Lang, Bartolome Moya, Dhruvitkumar Sutaria, Yuanyuan Jiao, Nirav Shah
15 April 2019 - P1833
Outer membrane permeability of 15 beta-lactams in multidrug-resistant Acinetobacter baumannii (MDR-AB) characterised via LC-MS/MS
Jürgen Bulitta, Xun Tao, Jieqiang Zhou, Yinzhi Lang, Bartolome Moya, Yuanyuan Jiao, Dhruvitkumar Sutaria, Nirav Shah, Tae Hwan Kim, Herbert Schweizer, Robert A. Bonomo, Richard E Lee, Arnold Louie, George Drusano, John Boyce, Deanna Deveson Lucas
15 April 2019 - P1832
First whole-cell assay to study the time-course of beta-lactams binding to penicillin binding proteins in Acinetobacter baumannii
Bartolome Moya, Dhruvitkumar Sutaria, Xun Tao, John Boyce, Deanna Deveson Lucas, Jieqiang Zhou, Yinzhi Lang, Yuanyuan Jiao, Nirav Shah, Tae Hwan Kim, Herbert Schweizer, Robert A. Bonomo, Richard E Lee, Arnold Louie, George Drusano, Jürgen Bulitta
23 April 2017 - EP0427
Equivalent efficacy and better safety of double beta-lactam vs. beta-lactam plus aminoglycoside combinations for Gram-negative infections - a systematic review of 12 randomized clinical trials
Yuanyuan Jiao, Bartolome Moya, Yuli Quian, Xun Tao, Jürgen Bulitta
22 April 2017 - P0237
Inactivation of penicillin-binding protein 2 is critical for killing Pseudomonas aeruginosa at high but not at low bacterial density
Bartolome Moya, Yuanyuan Jiao, Yuli Quian, Xun Tao, Arnold Louie, Jürgen Bulitta
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