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ESCMID Global 2024
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Guidelines
From the archive: ECCMID and more before 2010
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29 April 2024 - P2935
Effect of SCY-247, a second-generation triterpenoid antifungal, on growth kinetics and ultrastructure of Candida auris
Mahmoud A. Ghannoum, Lisa Long, Mohamed Seddiki, Rachael Gowen, Kyle Roberts, Tom Mccormick, Steve Wring, Katyna Borroto-Esoda, David Angulo
27 April 2024 - O0123
Increased virulence of pan-resistant Candida auris observed in a murine survival and fungal burden model comparing echinocandin-susceptible and pan-resistant strains
Mahmoud A. Ghannoum, Janet Herrada, Ali Elabbasi, Ahmed Gamal, Lisa Long, Tom Mccormick, Steve Wring, David Angulo
16 April 2023 - P2020
Evaluate the effect of ibrexafungerp alone and in combination with amphotericin B or posaconazole against Mucor strains using time kill kinetics and scanning electron microscopy
Lisa Long, Rachael Gowen, David Angulo, Nkechi Azie, Mahmoud A. Ghannoum
16 April 2023 - P2047
Evaluating the in vitro efficacy of ibrexafungerp (SCY-078) against isolates from clinical trial involving patients with fungal diseases that are refractory to or intolerant of standard antifungal treatment (FURI)
Fatima Zohra Abidi, Ahmed Gamal, Kristen Webster, Lisa Long, David Angulo, Nkechi Azie, Mahmoud A. Ghannoum
16 April 2023 - P2074
Open-label study to evaluate the efficacy and safety of SCY-078 (Ibrexafungerp) in patients with fungal diseases that are refractory to or intolerant of standard antifungal treatment (FURI)
Syed Faisal Mahmood, David Angulo, Michelle Middle, Nkechi Azie, Joveria Farooqi, Muhammad Irfan, Nousheen Iqbal, Ali Zubairi, Shazia Abrar, Ammara Muzammil
25 April 2022 - B0036
Oral ibrexafungerp outcomes by fungal disease in patients from 4th interim analysis of a phase III open-label study (FURI)
Barbara Alexander, Martin Hoenigl, Riina Richardson, Peter Pappas, Jose Vazquez, Marisa Miceli, George Thompson, Luis Ostrosky, Thomas Walsh, Patricia Munoz, Tihana Bicanic, Andres Spec, Nguyen Minh Hong, David Andes, Robert Krause, Rachel Miller, Paschalis Vergidis, Christoph Stephan, Thomas King, Nkechi Azie, David Angulo, Oliver Cornely
23 April 2022 - P1550
The FURI study: patient outcomes after treatment with oral ibrexafungerp based on prior antifungal therapy and patient enrollment criteria
Oliver Cornely, Thomas King, Nkechi Azie, David Angulo
23 April 2022 - L0246
Outcomes of oral ibrexafungerp in the treatment of 18 patients with Candida auris infections, from the CARES study
Richard Siebert, Thomas King, Nkechi Azie, David Angulo
23 April 2022 - P1562
Oral ibrexafungerp outcomes in patients with invasive candidiasis and candidaemia from the FURI and CARES Studies
Oliver Cornely, Peter Pappas, Thomas King, Nkechi Azie, David Angulo
16 April 2019 - L0010
Favorable Response to Oral Ibrexafungerp (formerly SCY-078) in Patients with Refractory Fungal Diseases, Interim Analysis by Pathogen from a Phase 3 Open-label Study (FURI)
Oliver A Cornely, Oliver A. Cornely, Luis Ostrosky-Zeichner, Rachel Miller, Andrej Spec, George Thompson, Thomas J. Walsh, Riina Richardson, Robert Krause, Peter G. Pappas, Kathleen Mullane, Caryn G. Morse, John W. Sanders, Günter Weiss, Oliver Witzke, Jose Vazquez, Marisa H. Miceli, Thomas Patterson, Martin Hoenigl, Barbara Alexander, David Angulo Gonzalez
15 April 2019 - O0740
Penetration of ibrexafungerp (formerly SCY-078) versus micafungin at the site of infection in an intra-abdominal candidiasis mouse model
Annie Lee, Brendan Prideaux, Minhee Lee, Matthew Zimmerman, Padmaja Paderu, Stephen Barat, David Angulo Gonzalez, David Perlin, Yanan Zhao
13 April 2019 - L0028
Successful Treatment of Two Patients with Candida auris Candidemia with the Investigational Agent, Oral Ibrexafungerp (formerly SCY-078) from the CARES Study
Deven Juneja, Omender Singh, Bansidhar Tarai, David Angulo Gonzalez
13 April 2019 - L0033
Favourable Clinical Outcome of Two Patients with Candida spp Spondylodiscitis treated with Oral Ibrexafungerp (formerly SCY-078) from the FURI Study
Philipp Koehler, Philipp Köhler, Oliver A. Cornely, David Angulo Gonzalez
25 April 2017 - P1713
Effect of SCY-078 on the pharmacokinetics of CYP2C8 substrate (rosiglitazone), results from a phase 1 clinical trial
Thomas Chen, David Angulo Gonzalez, George Atiee, Christy Corr, Michael Willett, M. Gail Murphy, Steven Wring
25 April 2017 - P1738
The effect of SCY-078 on the pharmacokinetics of tacrolimus, the results of a phase 1 drug-drug Interaction clinical trial
Thomas Chen, David Angulo Gonzalez, George Atiee, Christy Corr, Michael Willett, M. Gail Murphy, Steven Wring
25 April 2017 - OS0846
A prospective, phase 2, multicentre, open-label, randomized, comparative study to estimate the safety, tolerability, pharmacokinetics, and efficacy of oral SCY-078 vs standard-of-care following initial intravenous echinocandin therapy in the treatment of
Thomas Chen, Peter G. Pappas, John Pullman, George Thompson, Andrej Spec, Ellis Tobin, Jose Vazquez, David Angulo Gonzalez, Silvia Helou
24 April 2017 - EP0698
The emerging Candida auris: antifungal activity of SCY-078, a novel glucan synthesis inhibitor, on growth morphology and biofilm formation
Mahmoud A. Ghannoum, Emily Larkin, Christopher Hager, Jyotsna Chandra, Pranab Mukherjee, Mauricio Retuerto, Iman Salem, Lisa Long, Nancy Isham, Laura Kovanda, Katyna Borroto-Esoda, Steve Wring, David Angulo Gonzalez
22 April 2017 - EV0123
Evaluation of the antifungal activity of SCY-078 in combination with other antifungals against Aspergillus strains
Mahmoud A. Ghannoum, Lisa Long, Emily Larkin, Katyna Borroto-Esoda, Steve Wring, David Angulo Gonzalez
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