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28 April 2024 - P2423
Predictive performance of population pharmacokinetic models for model-informed precision dosing of meropenem in critically ill patients varied across different study settings
Iris K. Minichmayr, Sebastian Greppmair, Christoph Dorn, Alexander Brinkmann, Anka Roehr, Otto Frey, Albrecht Eisert, Christian Lanckohr, Christina Scharf, Michael Zoller, Markus Zeitlinger, Sebastian G. Wicha, Uwe Liebchen
2021
From therapeutic drug monitoring to model-informed precision dosing for antibiotics
Clin Pharm Ther. 2021 Apr;109(4):928-941. doi: 10.1002/cpt.2202
Sebastian G Wicha,  Anne-Grete Märtson,  Elisabet I Nielsen,  Birgit C P Koch,  Lena E Friberg,  Jan-Willem Alffenaar,  Iris K Minichmayr
09 July 2021 - 3863
Model-informed translation of in vitro meropenem effects against Pseudomonas aeruginosa to diverse clinical situations
Iris K. Minichmayr, I.K. Minichmayr, L.E. Friberg
15 April 2019 - O0829
Impact of single key components of intensified ceftaroline dosing on pharmacokinetic/pharmacodynamic target attainment
Iris K. Minichmayr, Sebastian Wicha, Peter Matzneller, Charlotte Kloft, Markus Zeitlinger
23 April 2018 - P1473
Murine model of chronic Pseudomonas aeruginosa lung infection: development and comparison to an acute pneumonia model
Iris K. Minichmayr, A. LEROY, C. Jacqueline, M. Davieau, A. Broquet, D. Boutoille, J. Caillon
21 April 2018 - P0176
Synergistic interaction of voriconazole and terbinafine against intrinsically azole-resistant Aspergillus calidoustus
Iris K. Minichmayr, E. Glampedakis, A. Coste, M. Aruanno, D. Bachmann, F. Lamoth
24 April 2017 - P1191
Target attainment of standard meropenem dosing in critically ill patients: High impact of renal function
Mario Fernandez Ruiz, Lisa Ehmann, Michael Zoller, Iris K. Minichmayr, Christina Scharf, Michael Vogeser, Lorenz Frey, Johannes Zander, Charlotte Kloft
23 April 2017 - EP0356
Development and validation of a dosing nomogram for continuous infusion of meropenem in critically ill patients
Iris K. Minichmayr, Otto R. Frey, Alexander Brinkmann, Anka Roehr, Jason Roberts, Charlotte Kloft
22 April 2017 - EV0448
Target-site specific pharmacokinetic/pharmacodynamic index values predicting linezolid efficacy in interstitial tissue space
Iris K. Minichmayr, Sebastian Wicha, Charlotte Kloft
11 April 2016 - P1192
AUC/MIC versus T>MIC: which PK/PD index is more indicative of linezolid efficacy in plasma and interstitial tissue space of septic patients with different weight?
Iris K. Minichmayr, Islam Ghazi, Minichmayr Iris, I. Minichmayr, S. Wicha, C. Kloft
11 April 2016 - P1249
Population pharmacokinetics of ceftaroline in healthy volunteers – comparison of target attainment achieved by standard versus intensified dosing
Iris K. Minichmayr, Minichmayr Iris, Huttner Angela, I. Minichmayr, M. Zeitlinger, P. Matzneller, C. Kloft
11 April 2016 - P1239
Pharmacokinetic/pharmacodynamic analysis of meropenem in critically ill patients
Mario Fernandez Ruiz, Ehmann Lisa, Zhang Liping, L. Ehmann, M. Zoller, C. Scharf, I. Minichmayr, M. Vogeser, L. Frey, J. Zander, C. Kloft
09 April 2016 - EV0448
Klebsiella pneumoniae isolates: a five-year study of mechanisms of carbapenem resistance
Antonios Stylianakis, Stylianakis Anthonios, Minichmayr Iris K., V. Papaioannou, A. Stylianakis, A. Kakiou, E. Koiliari, E. Maggou, D. Dimopoulos, K. Kafantogia, S. Tsiplakou
28 April 2015 - P1390
TDMx: a web application for bedside model-supported therapeutic drug monitoring to improve antibiotic therapy
Sebastian Wicha, Wicha, Sebastian G. *; Kees, Martin G.; Solms, Alexander; Minichmayr, Iris K; Kratzer, Alexander; Kloft, Charlotte;
27 April 2015 - P1131
Determinants of piperacillin clearance in critically ill patients receiving continuous infusion: comparison of cystatin C-based and alternative markers of renal function
Iris K. Minichmayr, Minichmayr, Iris K.*; Steinke, Thomas; Moritz, Stefan; Beck, Stefanie; Wicha, Sebastian G.; Kees, Martin G.; Kloft, Charlotte;
13 May 2014 - P1714
Impact of patient- and disease-related characteristics on plasma and target site pharmacokinetics of linezolid in four heterogeneous populations
Iris K. Minichmayr, Minichmayr, I.K.(1)*; Schaeftlein, A.(2); Zeitlinger, M.(3); Kloft, C.(1);
27 April 2013 - P927
Population pharmacokinetics of linezolid in diabetic patients with soft tissue infections: are standard doses adequate?
Iris K. Minichmayr, I.K. Minichmayr*, A. Schaeftlein, M. Zeitlinger, C. Kloft (Berlin, DE; Vienna, AT)
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