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ESCMID Global 2024
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From the archive: ECCMID and more before 2010
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23 April 2022 - P1305
Antitubercular activity of novel bacterial topoisomerase inhibitors with dioxygenated linkers
Jason Cummings, Yanran Lu, Richard Slayden, Mark Mitton-Fry
15 April 2019 - P1847
In vitro activity of BWC0977 (a novel bacterial topoisomerase inhibitor) and comparators against recent clinical and molecularly characterized Enterobacteriaceae and non-fermenter isolates from the United States and Europe
Michael Huband, Jill Lindley, Amy A. Watters, Holly K Becker, Vasanthi Ramachandran, Balasubramanian Venkataraman
15 April 2019 - P1849
In vitro activities of gepotidacin, a novel triazaacenaphthylene topoisomerase IV and DNA gyrase inhibitor, against Gram-negative bacteria and Staphylococcus saprophyticus
Shazad Mushtaq, Anna Vickers, Zahra Sadouki, Michelle Cole, Helen Fifer, Vivienne DoNascimento, Martin Day, Elizabeth De Pinna, Claire Jenkins, Gauri Godbole, Neil Woodford
15 April 2019 - P1844
BWC0977, a novel dual target topoisomerase inhibitor: potency, spectrum and mechanism of action
Radha Nandishaiah, Shahul Hameed Peer Mohamed, Sreevalli Sharma, Nainesh Katagihallimath, Nagakumar Bharatham, Anirudh Shanbhag, Sreenath Rajagopal, Purnendu Bhowmik, Prakruthi Amar, Riya Narjari, Vasanthi Ramachandran, Santanu Datta, Balasubramanian Venkataraman
15 April 2019 - P1845
In vitro activity of BWC0977, a novel bacterial topoisomerase inhibitor, and comparators against recent clinical Enterobacteriaceae and non-fermentor isolates from two hospitals in Bengaluru, India
Vasanthi Ramachandran, Savitha Raveendran, Teby Thomas, Maitrayee Sharma, Savitha Prabhumurthy, Sreenath Rajagopal, Savitha Nagaraj, Swathi Purighalla, Vijay Richard, Shahul Hameed Peer Mohamed, Balasubramanian Venkataraman
15 April 2019 - P1846
In vitro activity of BWC0977, a novel bacterial topoisomerase inhibitor, against molecularly characterised Enterobacteriaceae and non-fermentor isolates of the CDC collection and biodefense pathogens
Bala Subramanian, Nathan Wiederhold, Richard Slayden, Maria McElmeel, Thomas Patterson, Jason Cummings, Shahul Hameed Peer Mohamed, Vasanthi Ramachandran, Balasubramanian Venkataraman
15 April 2019 - P1850
Inhibiting bacterial topoisomerases via the ATP-binding site yields broad-spectrum antibacterial compounds with low resistance potential
Lucija Peterlin Mašič, Akos Nyerges, Martina Durcik, Nace Zidar, Žiga Skok, Janez Ilaš, Tamás Révész, Gábor Draskovits, Petra Szili, Anamarija Zega, Danijel Kikelj, Csaba Pál, Tihomir Tomašič
15 April 2019 - P1848
Design and synthesis of new DNA gyrase and topoisomerase IV inhibitors with broad spectrum antibacterial activity
Martina Durcik, Akos Nyerges, Žiga Skok, Nace Zidar, Janez Ilaš, Anamarija Zega, Päivi Tammela, Tamás Révész, Gábor Draskovits, Danijel Kikelj, Csaba Pál, Tihomir Tomašič, Lucija Peterlin Mašič
14 April 2019 - O0525
Dioxane-linked novel bacterial topoisomerase inhibitors
Mark Mitton-Fry, Linsen Li, Antony Okumu, Yanran Lu, Sandip Vibhute, Sheri Dellos-Nolan, Anthony English, Jack Yalowich, Daniel Wozniak
07 September 2018 - 135
Synthesis and Evaluation of Novel Bacterial Topoisomerase Inhibitors with Reduced hERG Inhibition
23 April 2017 - EP0381D
Antibacterial activity against fluoroquinolone-resistant clinical isolates of novel dual topoisomerase II inhibitors
Noemi D'Atanasio, Rosella Ombrato, Gabriele Magarò, Laura Di Sante, Carla Vignaroli, Claudio Milanese, Francesco Paolo Di Giorgio, Serena Tongiani
11 April 2016 - P1278
Novel class of dual topoisomerase II inhibitors: study on mode of action
Cristina Bartella, Gür Deniz, Bartella Cristina, C. Bartella, N. D'Atanasio, C. Apicella, F. Mancini, M. Vitiello, R. Ombrato, A. Capezzone de Joannon, G. Mangano, F. Garofolo, S. Tongiani
11 April 2016 - P1279
Biological profiling of novel bacterial topoisomerase inhibitors with broad-spectrum antibacterial activity
Emmanuel Moyo, Moyo Emmanuel, Poirel Laurent, E. Moyo, C. Charrier, A. Salisbury, V. Savage, H. Forward, R. Newman, N. Chaffer-Malam, R. Metzger, J. Cheung, R. Stovold, D. McGarry, M. Pichowicz, A. Lyons, R. Sigerson, I. Cooper, S. Best, A. Ratcliffe, N. Stokes
28 April 2015 - P1361
In vitro evaluation of novel bacterial topoisomerase inhibitors
Anne-Marie Salisbury, Salisbury, Anne-Marie *; Charrier, Cedric; Forward, Henry; Moyo, Emmanuel; Newman, Rebecca; Savage, Victoria; Metzger, Richard; Stovold, Rachel; Nelson, Gary; Clare, Daniel; Cooper, Ian; Finlayson, Jon; Lyons, Amanda; McGarry, David; Pichowicz, Mark; Sigerson, Ralph; Craighead, Mark; Best, Stuart; Ratcliffe, Andrew; Stokes, Neil;
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