The polyamino-isoprenic potentiator NV716 revives disused antibiotics against intracellular forms of infection by Escherichia coli, Klebsiella pneumoniae, and Acinetobacter baumannii
Antibiotic-antifungal combinatory pharmacodynamics against an in vitro inter-kingdom three-species biofilm model in the context of orthopaedic devices infection
The polyamino-isoprenyl compound NV716 resensitises old disused antibiotics against Pseudomonas aeruginosa (PA) by inhibiting efflux and disturbing outer membrane permeability
Strain-to-strain variations in the in vitro efficacy of a tri-enzymatic cocktail to prevent and disperse biofilms of bacterial species commonly associated with prosthetic joint infection
Influence of chromosomal mutations in genes encoding MtrCDE efflux, PorB1b porin, and PBP1 on susceptibility towards multiple antibiotic classes in clinical isolates of Neisseria gonorrhoeae
Activity of fluoroquinolones (finafloxacin, levofloxacin, ciprofloxacin) vs. that of imipenem against extracellular and intracellular forms of infection by Burkholderia thailandensis
Activity of combinations of an enzymatic cocktail (ENZ) with tobramycin (TOB), amikacin (AMK), ciprofloxacin (CIP), moxifloxacin (MXF), vancomycin (VAN) or linezolid (LDZ) against biofilms of clinical isolates from different ESKAPE pathogens
Oxazolidinones induce mitochondrial metabolism impairment at clinically-relevant concentrations in human megakaryocytic cell lines (UT7-WT and UT7-MPL)
Activity of the novel Fabl inhibitor Debio 1452 against intracellular forms of susceptible and resistant S. aureus: comparison with linezolid, vancomycin and daptomycin
Cooperation between active efflux and porin alteration is sufficient to confer high-level resistance to meropenem (MEM) in Pseudomonas aeruginosa (Pa) clinical isolates
Activities of amoxicillin (AMX), clarithromycin (CLR) and moxifloxacin (MXF) towards intracellular forms of Streptococcus pneumoniae with increasing mutant inhibitory concentrations (MICs): attempt at defining an intracellular susceptibility breakpoint
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