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17 April 2023 - P2264
Pharmacokinetics of BV100 after single ascending doses in healthy participants
17 April 2023 - P2258
Pharmacokinetics of BV100 after multiple ascending doses in healthy participants
23 April 2022 - P0135
The sulfoxide metabolite of ethionamide has antibacterial activity against Mycobacterium tuberculosis and is boosted by clinical candidate BVL-GSK098
15 April 2019 - P1839
Outer membrane protein targeting antibiotics: pharmacokinetics and in vivo efficacy of POL7306
15 April 2019 - P1843
Antimicrobial activity of POL7306 tested against clinical isolates of Gram-negative bacteria collected worldwide
15 April 2019 - P1836
Activity of murepavadin against colistin-resistant Pseudomonas aeruginosa clinical isolates
15 April 2019 - P1840
In vitro propensity of resistance development of POL7306, a new outer membrane protein targeting antibiotic
15 April 2019 - P1838
POL7306, a new outer membrane protein targeting antibiotic: the effect of testing parameter variations and body fluids on in vitro activity
25 April 2017 - OS1019
Pharmacokinetics and pharmacodynamics of murepavadin (POL7080) in neutropenic lung infection models
24 April 2017 - P1311
Pharmacokinetic of murepavadin (POL7080) and amikacin in a drug-drug interaction phase 1 study in healthy subjects
24 April 2017 - P1307
Population pharmacokinetics modelling of murepavadin (POL7080) and simulation of target attainment in a population with ventilator associated pneumonia due to infection with Pseudomonas aeruginosa
24 April 2017 - P1310
In-vitro drug transporter interaction studies with the outer membrane protein targeting anti-pseudomonal antibiotic murepavadin (POL7080)
24 April 2017 - P1309
Catabolism and excretion of the anti-pseudomonal antibiotic Murepavadin (POL7080) in humans
24 April 2017 - P1367
POL7001 is highly efficacious in the murine neutropenic lung infection model
24 April 2017 - P1308
Pharmacokinetic and efficacy analysis of murepavadin (POL7080) co-administered with standard-of-care (SoC) in a phase II study in patients with ventilator-associated pneumonia (VAP) due to suspected or documented Pseudomonas aeruginosa infection
11 April 2016 - P1307
Metabolism and excretion of the novel macrocycle antibiotic POL7080
11 April 2016 - P1308
Pharmacokinetics and safety of POL7080 in subjects with impaired renal function
11 April 2016 - P1309
Pharmacokinetics of POL7080 co-administered with standard of care (SoC) in patients with ventilator-associated pneumonia (VAP) due to suspected or documented Pseudomonas aeruginosa infection
09 April 2016 - P0345
Activity of novel antibiotic POL7080 against clinical isolates from a surveillance programme in CN (2012 and 2013)
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