In vivo efficacy of humanized pulmonary exposures of WCK 5222 (cefepime/zidebactam) in neutropenic murine lung infection caused by carbapenemase-producing Klebsiella pneumoniae (KP) and Acinetobacter baumannii (AB) with WCK 5222
In vitro activity of cefepime/zidebactam (WCK 5222) against a panel of MDR/XDR Pseudomonas aeruginosa isolates from India enriched with resistance to novel β-lactam/ β-lactamase inhibitor combinations
Selection of EUCAST disk potency for WCK 4282 (cefepime-tazobactam, FEP-TAZ) susceptibility testing against Enterobacterales and Pseudomonas aeruginosa
Selection of EUCAST disk potency for WCK 5222 (cefepime-zidebactam, FEP-ZID) susceptibility testing against Enterobacterales, Pseudomonas aeruginosa and Acinetobacter baumannii
Outer membrane protein targeting antibiotics (OMPTAs): investigation of the in vitro time-kill kinetics and rate of resistance development by serial passage
A novel beta-lactam enhancer Gram-negative antibiotic, zidebactam (ZID) - phenotypic and genotypic characteristics of ZID-selected mutants of Enterobacteriaceae - expressing Class C, KPC and NDM
Unraveling the cefepime-zidebactam synergy basis against metallo-beta-lactamase (MBL)-producing Pseudomonas aeruginosa through penicillin-binding protein (PBP) binding dynamics
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