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From the archive: ECCMID and more before 2010
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09 July 2021 - 833
A pharmacokinetically-based approach to predict anti-mutant efficacy of combined doripenem and levofloxacin therapy in in vitro model studies with Pseudomonas aeruginosa
Maria Golikova, M. Golikova (1), E. Strukova (1), K. Alieva (1), Y. Portnoy (1), A. Filimonova (1), S.H. Zinner (2), A. Firsov (1)
15 April 2019 - P2116
Linezolid and daptomycin combinations prevent selection of resistant Staphylococcus aureus mutants: multiple-dose simulations using an in vitro dynamic model
Stephen Zinner, Kamilla Alieva, Maria Golikova, Elena Strukova, Yury Portnoy, Alexander A. Firsov
21 April 2018 - P0253
Alternative predictors of staphylococcal resistance to linezolid
Ilda Czobor, K. Alieva, E. Strukova, M. Golikova, Y. Portnoy, S. Zinner, A. Firsov
21 April 2018 - P0252
Testing the mutant selection window hypothesis with Enterococcus faecium exposed to linezolid in an in vitro dynamic model
Kamilla Alieva, K. Alieva, M. Golikova, E. Strukova, Y. Portnoy, S. Dovzhenko, M. Kobrin, S. Zinner, A. Firsov
21 April 2018 - P0251
Comparative resistance studies using in vitro dynamic model: amoxicillin versus azithromycin against Streptococcus pneumoniae
Kamilla Alieva, M. Golikova, E. Strukova, K. Alieva, Y. Portnoy, S. Dovzhenko, M. Kobrin, S. Zinner, A. Firsov
24 April 2017 - P1203
The rationale for use of linezolid (L) and rifampicin (R) combinations to prevent selection of resistant Staphylococcus aureus mutants: multiple-dose simulation using an in-vitro dynamic model
Alexander A. Firsov, Maria Golikova, Elena Strukova, Yury Portnoy, Stephen Zinner
24 April 2017 - P1204
Concentration-resistance relationships with Staphylococcus aureus exposed to linezolid in an in-vitro dynamic model
Alexander A. Firsov, Kamilla Alieva, Elena Strukova, Maria Golikova, Yury Portnoy, Stephen Zinner
22 April 2017 - EV0445
A new approach to predict anti-staphylococcal effects of antibiotic combinations using an in-vitro dynamic model
Alexander A. Firsov, Maria Golikova, Elena Strukova, Yury Portnoy, Stephen Zinner
11 April 2016 - P1196
Comparative pharmacodynamics of ceftaroline and linezolid against Staphylococcus aureus in an in vitro dynamic model
Alexander A. Firsov, De Velde Femke, Firsov Alexander A., M. Golikova, S. Dovzhenko, M. Kobrin, Y. Portnoy, S. Zinner, A. Firsov
11 April 2016 - P1195
Testing the mutant selection window hypothesis in Staphylococcus aureus resistance studies with linezolid using a mixture of antibiotic-susceptible cells and resistant mutants in an in vitro dynamic model
Kamilla Alieva, Alieva Kamilla, Goutelle Sylvain, K. Alieva, E. Strukova, Y. Portnoy, M. Golikova, S. Zinner, A. Firsov
09 April 2016 - EV0644
Endpoints in bacterial resistance studies using in vitro dynamic models: an integral parameter versus a point parameter
Alexander A. Firsov, Firsov Alexander A., A. Firsov, M. Golikova, E. Strukova, Y. Portnoy, S. Zinner
25 April 2015 - EV0055
Can clinical dosing regimens provide "anti-mutant" fluoroquinolone concentrations? Predictions using in vitro dynamic models
Alexander A. Firsov, Firsov, Alexander *; Strukova, Elena; Portnoy, Yury; Shlykova, Darya; Zinner, Stephen;
25 April 2015 - EV0054
Strain-specific concentration-resistance relationships with ciprofloxacin-exposed Pseudomonas aeruginosa: is it possible to predict the enrichment of resistant mutants if the same bacterial species?
Alexander A. Firsov, Strukova, Elena *; Portnoy, Yury; Shlykova, Darya; Zinner, Stephen; Firsov, Alexander ;
13 May 2014 - P1691
Predicting bacterial resistance using the time inside the mutant selection window: pros and cons
Alexander A. Firsov, Firsov, A.(1)*; Portnoy, Y.(1); Strukova, E.(1); Shlykova, D.(1); Zinner, S.(2);
13 May 2014 - P1732
Predictors of fluoroquinolone resistance in Pseudomonas aeruginosa: area under the curve related to either MIC or the mutant prevention concentration
Alexander A. Firsov, Strukova, E.(1)*; Shlykova, D.(1); Portnoy, Y.(1); Zinner, S.(2); Firsov, A.(1);
27 April 2013 - P929
Fluoroquinolone resistance in Escherichia coli: search for the optimal predictor using in vitro dynamic models
Alexander Firsov, E. Strukova, D. Shlykova, Y. Portnoy, S. Zinner, A. Firsov* (Moscow, RU; Cambridge, US)
01 April 2012 - P1610
Anti-mutant potentials of doripenem, imipenem and ciprofloxacin against Pseudomonas aeruginosa examined using an in vitro dynamic model
Alexander A. Firsov, S. Zinner*, D. Gilbert, K. Greer, Y. Portnoy, A. Firsov (Cambridge, US; Moscow, RU)
01 April 2001
Interspecies prediction of the antimicrobial effects of gemifloxacin and ciprofloxacin on Haemophilus influenzae based on the comparative pharmacodynamic studies in an in vitro model
S. Vostrov, I. Lubenko, Y. Portnoy, S. Zinner, A. Firsov
01 April 2001
Different integral endpoints of the total antimicrobial effect at clinically achievable ratios of area under the curve to MIC: the pharmacodynamics of gemifloxacin with Moraxella catarrhalis in an in vitro dynamic model
A. Firsov, I. Lubenko, S. Vostrov, Y. Portnoy, S. Zinner
01 April 2001
Preventing the production of resistant mutants of Staphylococcus aureus with moxifloxacin and levofloxacin: dose ranging studies using an in vitro dynamic model
I. Lubenko, S. Vostrov, Y. Portnoy, S. Zinner, A. Firsov
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