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ESCMID Global 2024
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From the archive: ECCMID and more before 2010
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24 April 2017 - P1364
In-vitro activity of the novel fluorocycline TP-6076 against carbapenem non-susceptible Acinetobacter baumannii
Ine Wouters, Harald Seifert, Danuta Stefanik, Joyce Sutcliffe, Paul G Higgins
11 April 2016 - P1310
TP-6076 is efficacious in a mouse pneumonia model with carbapenem-resistant Acinetobacter baumannii (CRAB) and retains potency against common tetracycline-resistance mechanisms
Trudy Grossman, Dale Glenn, Grossman Trudy, T. Grossman, C. Fyfe, K. Kerstein, X. Xiao, C. Sun, J. Newman, P. Nguyen, M. Pulse, W. Weiss, J. Dumas, J. Sutcliffe
09 April 2016 - P0265
In vitro activity of eravacycline and comparators against Acinetobacter baumannii, including carbapenem-resistant strains, and Stenotrophomonas maltophilia isolated from patients in Europe
Patrick Scoble, Scoble Patrick, Brodrick Hayley, M. Bassetti, I. Morrissey, T. Grossman, K. Luepke, P. Scoble, J. Sutcliffe
09 April 2016 - P0342
Eravacycline in vitro activity against clinical isolates obtained from urinary and gastro-intestinal sources, including drug-resistant pathogens, from patients in Europe
Hina Patel, Snyder Jessica, Patel Hina, M. Bassetti, I. Morrissey, T. Grossman, M. Olesky, H. Patel, J. Sutcliffe
09 April 2016 - P0343
In vitro activity of eravacycline and comparators in Gram-negative organisms, including drug-resistant phenotypes, isolated from respiratory sources in Europe
Hina Patel, Patel Hina, Kulikalova Elena, M. Bassetti, I. Morrissey, T. Grossman, M. Olesky, H. Patel, J. Sutcliffe
09 April 2016 - P0344
In vitro activity of eravacycline and comparators against Enterobacteriaceae, including subgroups of strains with resistance to carbapenems or 3rd/4th-generation cephalosporins, isolated from patients in Europe
Patrick Scoble, Souza Dilair, Scoble Patrick, M. Bassetti, I. Morrissey, T. Grossman, K. Luepke, P. Scoble, J. Sutcliffe
27 April 2015 - P1022
Identification of Klebsiella pneumoniae genes involved in tigecycline-resistance using transposon mutagenesis
Trudy Grossman, Fyfe, Corey; Norris, Dionna; Sutcliffe, Joyce; Grossman, Trudy *;
25 April 2015 - P0054
TP-076 is active in vitro against biofilms formed by a panel containing fluoroquinolone-resistant and susceptible uropathogenic Escherichia coli clinical isolates
Trudy Grossman, Kerstein, Kathy; Sutcliffe, Joyce; Grossman, Trudy *;
25 April 2015 - P0243
In vitro activities of novel tetracyclines against molecularly characterized carbapenem-resistant Gram-negative pathogens
Trudy Grossman, Grossman, Trudy *; Clark, Roger; Xiao, Xiao-Yi; Fyfe, Corey; Sutcliffe, Joyce;
25 April 2015 - P0244
Efficacy evaluation of TP-271, a novel fluorocycline, in a neutropenic murine pneumonia model against susceptible and resistant Gram-positive pathogens
Timothy Murphy, Weiss, William *; Murphy, Timothy; Pulse, Mark; Nguyen, Phung; Valtierra, David; Peterson, Kelly; Silva, Jessica; Simecka, Jerry; Sutcliffe, Joyce; Grossman, Trudy;
12 May 2014 - P1228
Multi-locus sequence typing of Escherichia coli isolates from a phase 2 complicated intra-abdominal trial for eravacycline
Joyce Sutcliffe, Fyfe, C.(1); Grossman, T.(1); Tavares, P.(1); Sutcliffe, J.(1)*;
10 May 2014 - P0109
Eravacycline protects in a Bacillus anthracis-infected New Zealand white rabbit treatment model
Joyce Sutcliffe, Sutcliffe, J.(1)*; Selden, J.(1); Gooldy, M.(2); Pawlowski, D.(2); Radcliff, A.(2); Edwards, K.(2); Gillum, K.(3);
10 May 2014 - P0111
TP-271, a novel fluorocycline, is efficacious in a treatment model of aerosolised Francisella tularensis infection in BALB/c mice
Trudy Grossman, Grossman, T.(1)*; Lin, W.(2); Siefkas-Patterson, K.(2); Sutcliffe, J.(1);
10 May 2014 - P0299
In vitro potency of novel, fully synthetic tetracyclines against MDR Gram-negative pathogens, including carbapenem-resistant Enterobacteriaceae
Xiaoyi Xiao, Xiao, X.(1)*; Sun, C.(1); Hunt, D.(1); Clark, R.(1); Fyfe, C.(2); Kerstein, K.(2); Grossman, T.(2); Sutcliffe, J.(2);
10 May 2014 - P0300
In vivo efficacy of novel, fully synthetic tetracyclines in a murine lung infection model challenged with KPC-producing Klebsiella pneumoniae
Xiaoyi Xiao, Grossman, T.(1); Fyfe, C.(1); Kerstein, K.(1); Sun, C.(2); Hunt, D.(2); Clark, R.(2); Xiao, X.(2)*; Sutcliffe, J.(1);
29 April 2013 - P2107
Time to defervescence as an early marker of clinical response in patients with complicated intra-abdominal infections treated with eravacycline or ertapenem
Patrick Horn, P. Horn*, J. Sutcliffe, S. Walpole (Watertown, US)
28 April 2013 - O277
Characterisation of baseline pathogens and microbiological eradication in a phase 2 trial for treatment of complicated intra-abdominal infections comparing eravacycline (TP-434) to ertapenem
Joyce Sutcliffe, C. Fyfe, J. Deane, T.H. Grossman, P. Horn, G. Moore, D. Sahm, J. Studeny, S. Walpole, J. Sutcliffe* (Watertown, Chantilly, US)
28 April 2013 - P1641
The fluorocycline TP-271 is potent against major complicated community-acquired bacterial pneumonia (CABP) pathogens
Trudy Grossman, T.H. Grossman*, C. Fyfe, W. O'Brien, D.E. Low, M.B. Minyard, K. Waites, J. Dubois, J.A. Sutcliffe (Watertown, US; Toronto, CA; Birmingham, US; Sherbrooke, CA)
01 April 2012 - P1425
Mouse pharmacokinetics, dose fractionation and efficacy of TP-559, a novel tetracycline with anti-Pseudomonas activity, in murine infection models challenged with Pseudomonas aeruginosa
Joyce Sutcliffe, J. Sutcliffe*, X. Xiao, R. Clark, T. Grossman (Watertown, US)
01 April 2012 - P1426
The intravenous pharmacokinetics and efficacy of a novel tetracycline TP-433 in murine infection models challenged with Pseudomonas aeruginosa
Joyce Sutcliffe, Y. Deng, T. Grossman, R. Clark, X. Xiao, J. Sutcliffe* (Watertown, US)
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